US 10,588,873 B2Granted

Topical antifungal compositions

AssigneeExodos Life Sciences LP

InventorsServet Buyuktimkin, Nadir Buyuktimkin, James L. Yeager

Life of this patent

Estimating the term…

Abstract

Aqueous, topical compositions contain an allylamine or an azole as an antifungal agent together with a lactate ester, an organic acid (pKa 3.8-5), ethanol, water, and a cationic galactomannan gum.

Claims16

Dependent claims

A topical gel composition which comprises an antifungal agent selected from the group consisting of terbinafine, amorolfine, and efinaconazole, a lactate ester of a C2 to C16 saturated aliphatic alcohol, an organic acid having a pKa value in the range of about 3.8 to about 5, ethanol, water, and a cationic galactomannan gum.

Dependencies are inferred from the claim text.

Facts

Application: 16/255,271Filed 23 Jan 2019 · continuation in part
Priority: 7 Oct 2015
Published: US 2019/0151260 A123 May 2019
Granted: 17 Mar 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 31/137
Having aromatic rings , e.g. ketamine, nortriptyline: arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/06
Medicinal preparations characterised by special physical form: ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
A61K 31/454
Containing further heterocyclic ring systems: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone

Family

Application62/238,464Us provisional application · filed 7 Oct 2015
PCT/US2016/055978Parent of this continuation-in-part · filed 7 Oct 2016
US 2019/0151260 A1Pre-grant publication · published 23 May 2019
Application15/760,390Parent of this continuation-in-part
US 10,272,054 B2Parent of this continuation-in-part
US 2018/0256516 A1Published application
US 10,588,873 B2This patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

Aqueous, topical compositions contain an allylamine or an azole as an antifungal agent together with a lactate ester, an organic acid (pKa 3.8-5), ethanol, water, and a cationic galactomannan gum.

Facts

Application

16/255,271Filed 23 Jan 2019 · continuation in part

Priority

7 Oct 2015

Published

US 2019/0151260 A123 May 2019

Granted

17 Mar 2020

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 31/137
Having aromatic rings , e.g. ketamine, nortriptyline: arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/06
Medicinal preparations characterised by special physical form: ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
A61K 31/454
Containing further heterocyclic ring systems: containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone

Family

Application62/238,464Us provisional application · filed 7 Oct 2015

PCT/US2016/055978Parent of this continuation-in-part · filed 7 Oct 2016

US 2019/0151260 A1Pre-grant publication · published 23 May 2019

Application15/760,390Parent of this continuation-in-part

US 10,272,054 B2Parent of this continuation-in-part

US 2018/0256516 A1Published application

US 10,588,873 B2This patent

From the US filing history. Foreign family members aren’t listed.