Intraocular drug delivery device and associated methods
AssigneeUniversity of Utah Research Foundation
InventorsBalamurali K. Ambati, Bruce K. Gale, Srinivas Rao Chennamaneni
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Abstract
Devices, systems, and methods for delivery of an active agent from the lens capsule to a posterior segment of the eye of a subject can include an intraocular active agent delivery device including an active agent dispersed within a biodegradable active agent matrix. The active agent includes dexamethasone and the delivery device is adapted to fit within a lens capsule or ciliary sulcus of an eye. The delivery device can be inserted into the lens capsule or ciliary sulcus of an eye during cataract surgery or for treatment of uveitis.
Claims24
A method of delivering an active agent to a posterior segment of an eye of a subject, comprising:
- placing a biodegradable active agent matrix within a lens capsule of the subject to deliver the active agent to the posterior segment of the eye, said biodegradable active agent matrix comprising an active agent in an amount to deliver a therapeutically effective dose of the active agent to the posterior segment of the eye from the lens capsule;
- and
- delivering the therapeutically effective dose of the active agent to the posterior segment of the eye from the lens capsule.
Dependencies are inferred from the claim text.