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US 10,588,694 B1Granted
Devices and methods for generation of subsurface micro-disruptions for biomedical applications
OwnerJoseph Neevinventor
Life of this patent
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Abstract
A device comprises an energy source capable of generating short bursts of energy at a variable pulse repetition rates. The repetition rates range from a single shot to several hundred Mega-Hertzs so that selective, three dimensional interactions with a volumetric zone of skin or issue can be created substantially without damage or substantial changes to overlying or underlying or surrounding tissue or skin. A method and a device for treating targeted material and targeted tissue are described.
Claims27
A device for treatment of soft tissue, comprising
- an electromagnetic energy beam generator that produces at least one beam of electromagnetic energy, wherein the at least one beam comprises pulses with pulse durations from 10 femtoseconds to 10 nanoseconds, wherein said pulses have pulse rep rates between 10 MHz and 100 MHz, and each pulse has at least 0.1 nanojoule of energy;
- an optic assembly configured to redirect the source beam in space;
- and
- a mechanism that displaces the optic assembly by increments of less than 500 μm in a z direction.
1 more element
A device for treatment of tissue, comprising:
- an electromagnetic energy beam generator that produces at least one source beam of electromagnetic energy, wherein the source beam comprises pulses with pulse durations from 10 femtoseconds to 10 nanoseconds;
- an optic configured to redirect the source beam in space and to focus the source beam to a spot size having a diameter of 25 micrometers or more;
- a mechanism that displaces the optic by increments of less than 500 μm in a z direction;
- and
- a controller configured to control movement of the optic to redirect the source beam, the controller programmed to redirect the source beam between pulses to create complex subsurface patterns in targeted tissue;
- wherein the beam has sufficient energy to create a disruption in the continuity of the targeted tissue, but the energy of the beam is insufficient to cause tissue damage extending more than 5 micrometer beyond the tissue disruption.
3 more elements
A device for treatment of tissue, comprising:
- an electromagnetic energy beam generator that produces at least one source beam of electromagnetic energy, wherein the source beam comprises pulses with pulse durations from 10 femtoseconds to 10 nanoseconds, wherein the electromagnetic energy beam generator emits the pulses at pulse repetition rates from 0.001 Hz to about 1 MHz, and the pulse energy is from 0.01 microjoule to 10 joule;
- an optic configured to redirect the source beam in space and to focus the source beam to a spot size having a diameter of 25 micrometers or more;
- and
- a controller configured to control movement of the optic to redirect the source beam, the controller programmed to redirect the source beam between pulses to create complex subsurface patterns in targeted tissue while preventing the coalescence of more than 100 subsurface disruptions into a structural discontinuity;
- wherein the beam has sufficient energy to create at least one disruption in the continuity of the targeted tissue.
2 more elements
Dependencies are inferred from the claim text.