Connected fasteners, delivery device and method

An assembly for forming a fold of tissue, comprising:

• a device having a body and a tissue chamber coupled to the body, the tissue chamber being expandable, the device also having a plurality of tissue ports configured to draw a fold of tissue into each of the tissue ports using suction, the tissue ports being positioned along the tissue chamber so that the fold of tissue extends into the tissue chamber, the device also having a plurality of fasteners and a flexible filament carried by the body, wherein each fastener is slidably mounted on a stylet and configured to be delivered through the fold of tissue extending into the tissue port and held in the tissue port using suction, the flexible filament being coupled to each of the plurality of fasteners and extending through one of the tissue ports and entering another of the tissue ports prior to deployment, and a tensioning device implanted inside the body to apply tension on the flexible filament and thereby pull on the fasteners and moving the first and second folds of tissue towards one another and securing the flexible filament with a knot inside the body.