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US 10,577,634 B2Granted
Bioconversion process for producing nylon-7, nylon-7,7 and polyesters
AssigneeInvista North America S.A.R.L.
InventorsPaul S. Pearlman, Changlin Chen, Adriana L. Botes, Alex Van Eck Conradie, Benjamin D. Herzog
Life of this patent
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Abstract
Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.
Claims13
A method of converting a compound, the method comprising:
- providing a recombinant host cell expressing a heterologous thioesterase that catalyzes the thioester hydrolysis of pimeloyl-CoA (PCoA) to pimelic acid (PA), wherein the thioesterase is in EC 3.1.2.-;
- and
- contacting PCoA with the thioesterase, wherein PA is produced.
A method of converting a compound, the method comprising:
- providing a recombinant host cell expressing a heterologous thioesterase that catalyzes the thioester hydrolysis of pimeloyl-CoA (PCoA) to pimelic acid (PA), wherein the thioesterase is in EC 3.1.2.- or is a thioesterase encoded by a yciA gene;
- and
- contacting PCoA with the thioesterase, wherein PA is produced.
Dependencies are inferred from the claim text.