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US 10,577,337 B2Granted
Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
AssigneeRomark Laboratories L.C.
InventorsJean-Francois Rossignol, Andrew Stachulski
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Abstract
Prodrugs of tizoxanide, an analogue or salt thereof are disclosed. The prodrugs have an ester moiety comprising an amino acid moiety, and increase the bioavailability of the tizoxanide, an analogue or salt thereof. Compositions and methods of treating an intracellular protozoan infection, a viral infection or a cancer are also disclosed.
Claims11
A compound having formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.