Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists

A pharmaceutical composition comprising:

• a) a compound of the formula:
• wherein:
• A is C—OH or N;
• R′ is hydrogen, alkyl(C≤8), or substituted alkyl(C≤8);
• and
• X and Y are each independently cyano, halo, fluoroalkoxy(C1-2), alkyl(C1-2), or fluoroalkyl(C1-2), with the proviso that X and Y are not both cyano or alkyl(C1-2),
• or a pharmaceutically acceptable salt or tautomer of the above formula;
• and
• b) an excipient,
• wherein the carbon atom labeled β is in the S configuration.