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US 10,570,185 B2Granted
Method to detect autoantibody reactivity for deamidated insulin autoantigen in diabetes
AssigneeNorthwestern University
InventorsJing Jin, Xunrong Luo, Grazia Aleppo
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Abstract
Provided herein are epitopes and mimotopes thereof useful in the diagnosis and treatment of type 1 diabetes (T1D), as well as antibodies recognizing such epitopes, and diagnostics, therapeutics, kits, and methods of use thereof.
Claims5
A composition comprising a peptide or polypeptide comprising a sequence selected from SEQ ID NOs:
- 102 and 104-111 linked to a detectable label or attached to a solid surface.
A composition comprising a peptide or polypeptide consisting of SEQ ID NO:
- 101 linked to a detectable label or attached to a solid surface.
A composition comprising a peptide or polypeptide consisting of SEQ ID NO:
- 103 linked to a detectable label or attached to a solid surface.
Dependencies are inferred from the claim text.