Plant virus particles for delivery of photosensitive agents
AssigneeCase Western Reserve University
InventorNicole F. Steinmetz
Life of this patent
Estimating the term…
Abstract
Photodynamic virus particles including a plant virus particle associated with a photosensitizing agent are described. Methods of treating cancer in a subject by administering to the subject a therapeutically effective amount of the photodynamic virus particles and illuminating a cancer-bearing region of the subject to activate the photodynamic virus particles are also described.
Claims9
A photodynamic virus particle, comprising a tobacco mosaic virus particle associated with a zinc ethynyl porphyrin wherein the zinc ethynyl porphyrin is associated with the tobacco mosaic virus particle through electrostatic interaction.
A method of treating cancer in a subject by administering to the subject a therapeutically effective amount of photodynamic virus particles comprising a tobacco mosaic virus particle associated with a zinc ethynyl porphyrin, and illuminating a cancer-bearing region of the subject to activate the photodynamic virus particles, wherein the zinc ethynyl porphyrin is associated with the tobacco mosaic virus particle through electrostatic interaction.
Dependencies are inferred from the claim text.