US 10,544,439 B2Granted

Hexuronate C4-epimerase variant having improved D-tagatose conversion activity, and D-tagatose production method using same

AssigneeCj Cheiljedang Corporation

InventorsSung Jae Yang, Young Mi Lee, Il Hyang Park, Chan-Hyoung Lee, Hyun Kug Cho, Seong Bo Kim, Yang Hee Kim, Seung Won Park

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Abstract

Provided are a hexuronate C4-epimerase variant with improved activity in converting D-fructose by D-tagatose of hexuronate C4-epimerase and a method for production of D-tagatose using them.

Claims15

Dependent claims

A hexuronate C4-epimerase variant comprising an amino acid sequence having at least 80% sequence identity to SEQ ID NO:

1, wherein said variant comprises a mutation at a position corresponding to tyrosine (Y)-403 amino acid residue of SEQ ID NO:
1.

Dependencies are inferred from the claim text.

Facts

Application: 15/759,511Filed 31 Jul 2017
Priority: KR 10-2016-009750029 Jul 2016
Published: US 2019/0338329 A17 Nov 2019
Granted: 28 Jan 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C12N 9/90
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes: isomerases
C12P 19/02
Preparation of compounds containing saccharide radicals: monosaccharides
C12P 19/24
Preparation of compounds containing saccharide radicals: produced by the action of an isomerase, e.g. fructose
C12Y 501/02
Racemaces and epimerases: acting on hydroxy acids and derivatives

Family

US 2019/0338329 A1Pre-grant publication · published 7 Nov 2019
US 10,544,439 B2This patent

From the US filing history. Foreign family members aren’t listed.

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