Compositions and methods for treating bone defects
AssigneeUniversity of Louisville Research Foundation, Inc.
InventorsMichael J. Voor, Robert L. Burden, Jr.
Life of this patent
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Abstract
A bone graft composition includes a biologically-resorbable cement and a plurality of processed bone particles, where each of the bone particles have a shape configured to interconnect with adjacent bone particles. A method for treating a bone defect using the bone graft compositions includes providing the bone graft composition and administering an effective amount of the bone graft composition to a site of a bone defect in a subject. Kits including a biologically-resorbable cement powder and a plurality of processed bone particles are also provided.
Claims19
A bone graft composition, comprising:
- a biologically-resorbable cement;
- and
- a plurality of processed interconnecting bone particles, each of the interconnecting bone particles being cut from an intact whole bone or portion thereof, each of the interconnecting bone particles having larger dimensions at its ends compared to its center, and each of the interconnecting bone particles having a shape configured to interconnect with adjacent interconnecting bone particles,
- wherein the bone graft composition is configured to form a network of interconnected pathways or channels due to interconnected adjacent interconnecting bone particles, wherein the network of interconnected pathways or channels are configured to allow for cells and fluids to infiltrate the bone graft composition.
A kit, comprising:
- a biologically-resorbable cement powder;
- and
- a plurality of processed interconnecting bone particles, each of the interconnecting bone particles being cut from an intact whole bone or portion thereof, each of the interconnecting bone particles having lamer dimensions at its ends compared to its center, and each of the interconnecting bone particles having a shape configured to interconnect with adjacent interconnecting bone particles,
- wherein the plurality of processed interconnecting bone particles, when combined with the biologically-resorbable cement powder, are configured to form a network of interconnected pathways or channels due to interconnected adjacent interconnecting bone particles.
Dependencies are inferred from the claim text.