Abuse resistant formula
AssigneeEmplicure AB
InventorsSusanne Bredenberg, Anna Dahlgren, Anders Sågström, Håkan Engqvist
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Abstract
There is provided a sustained-release pharmaceutical composition comprising a solid, continuous network comprising an excipient with a high mechanical strength, which network also comprises pores, within which pores is interspersed a mixture of an active ingredient and a film-forming agent, characterised in that said pores are formed during the production of the composition. Compositions of the invention find particularly utility as abuse-resistant formulations comprising opioid analgesics that may be employed in the treatment of chronic pain.
Claims19
A sustained-release pharmaceutical composition comprising a solid, continuous network with a high mechanical strength, which network comprises an excipient, which network also comprises secondary pores, within which secondary pores is interspersed a mixture of an active ingredient and a film-forming agent, wherein the secondary pores are formed by physically and/or chemically bonding together the surfaces of particles of the excipient in the presence of said mixture, characterised in that said secondary pores are formed during the production of the composition wherein the excipient is based on one or more ceramic materials or one or more geopolymeric materials or combinations thereof.
Dependencies are inferred from the claim text.