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US 10,539,550 B2Granted
Exposure system
AssigneeInhalation Sciences AB
InventorPer Gerde
Life of this patent
Estimating the term…
Abstract
The invention relates to methodologies of obtaining a controlled exposure of an aerosol to a model material. The invention also provides an exposure cap and a system for studying or predicting the interaction between a model material, e.g. a cell, and an aerosolized agent. The controlled exposure of the aerosol to the model material, makes is possible to accurately calculate the mass-balance of the aerosol exposure.
Claims8
A method of obtaining a controlled exposure of a model material to an aerosol comprising the steps of;
- i. providing a container comprising the model material;
- ii. inserting an exposure cap into said container so as to obtain a substantially sealed environment during the exposure;
- iii. introducing a controlled aerosol flow to an upper part of the exposure cap and transporting the aerosol towards the surface of the model material with a flow rotating around a central axis of the exposure cap;
- iv. admitting the aerosol to contact the model material, while shielding the model material container from aerosol contact;
- and
- v. transporting remaining aerosol away from the model material surface in an axially upwards directed separate flow.
3 more elements
Dependencies are inferred from the claim text.