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US 10,538,591 B2Granted
Anti-fibulin-3 antibodies and uses thereof
AssigneeThe Brigham and Women's Hospital, Inc.
InventorsMariano S. Viapiano, Nandhu Mohan Sobhana, Ennio Antonio Chiocca
Life of this patent
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Abstract
Embodiments described herein provide anti-fibulin-3 antibodies, recombinant proteins that bind specifically to fibulin-3, compositions and the treatment methods comprising these antibodies and recombinant proteins.
Claims9
A T-cell or a Natural Killer (NK) cell comprising a chimeric antigen receptor (CAR) protein comprising an antigen-binding region of an anti-Fibulin-3 monoclonal antibody, the antigen-binding region comprising the amino acid sequences SEQ ID NO:
- 5-10.
Dependencies are inferred from the claim text.