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US 10,538,575 B2Granted
Soluble IGF receptor Fc fusion proteins and uses thereof
OwnerPnina Brodt, Bernard Massie +1inventors
InventorsPnina Brodt, Bernard Massie, Traian Sulea
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Abstract
There are described herein novel soluble IGF receptor Fc fusion proteins and compositions and methods of use thereof for treating angiogenesis associated disorders and malignant disease, such as cancer and metastasis, wherein the fusion proteins bind specifically to IGF-1 or IGF-2.
Claims13
A fusion protein comprising the sequence set forth in SEQ ID NO:
- 12 or SEQ ID NO:
- 16.
Dependencies are inferred from the claim text.