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US 10,538,545 B2Granted
Dinitrosyl iron complex, pharmaceutical composition comprising the same, composite material comprising the same, and uses thereof
AssigneeChung Yuan Christian University
InventorsTsai-Te Lu, Hsiao-Wen Huang, Chia-Her Lin, Yu-Ting Tseng, Wen-Feng Liaw, Hsi-Ya Huang, Show-Jen Chiou
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Abstract
Disclosed herein are novel compounds of formula (I) and (II), each of which may serve as a reagent to deliver nitric oxide (NO) and a therapeutic agent to treat NO-associated diseases. Also disclosed are a pharmaceutical composition comprising the compound of formula (I) or (II), a composite material comprising the compound of formula (I) or (II), and the uses thereof.
Claims2
A compound of formula (II),
- or its pharmaceutically acceptable salt or solvate, wherein,
- R′ is —NH2, —NO2, or —C6H5;
- and
- y is an integer between −2 to +2.
1 more element
Dependencies are inferred from the claim text.