Back to results
US 10,538,522 B2Granted
Brassinosteroid mimetics
AssigneeThe Regents of the University of California
InventorPaul Brian Larsen
Life of this patent
Estimating the term…
Abstract
The disclosure provides brassinosteroid mimetics and method of using such mimetics.
Claims9
A method to activate the brassinosteroid response in a plant, comprising applying a compound of Formula I(a) to the plant or in the root zone of the plant, wherein Formula I(a) comprises:
- wherein,
- R2, R3, R5, R7, R10-R14 are independently selected from H, D, NH2, —O-alkyl, —O-ether, SH, optionally substituted (c1-C12)alkyl, optionally substituted hetero(C1-C12)alkyl, optionally substituted (C2-C12)alkenyl, optionally substituted hetero(C2-C12)alkenyl, optionally substituted (C2-C12)alkynyl, optionally substituted hetero(C2-C12)alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, hydroxyl, halo, imine, amide, nitro, nitroso, nitrile, isocyanate, ester, aldehyde, ketone, carboxyl, thiol, thionyl, and sulfonyl;
- and
- R15 is an optionally substituted (C1-C6)alkyl, an optionally substituted hetero-(C1-C6)alkyl, an optionally substituted (C2-C6)alkenyl, an optionally substituted hetero-(C2-C6)alkenyl, an optionally substituted (C2-C6)alkynyl, or an optionally substituted hetero-(C1-C6)alkynyl, a cycloalkyl, an aryl, and a heterocycle.
1 more element
A composition for promoting plant growth comprising a brassinosteroid mimetic as set forth in Formula I(a) in a suitable delivery vehicle, wherein Formula I(a) comprises:
- wherein,
- R2, R3, R5, R10-R14 are independently selected from H, D, NH2, —O-alkyl, —O-ether, SH, optionally substituted (c1-C12)alkyl, optionally substituted hetero(C1-C12)alkyl, optionally substituted (C2-C12)alkenyl, optionally substituted hetero(C2-C12)alkenyl, optionally substituted (C2-C12)alkynyl, optionally substituted hetero(C2-C12)alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, hydroxyl, halo, imine, amide, nitro, nitroso, nitrile, isocyanate, ester, aldehyde, ketone, carboxyl, thiol, thionyl, and sulfonyl;
- R7 is selected from D, NH2—O-alkyl, —O-ether, SH, optionally substituted (c1-C12)alkyl, optionally substituted hetero(C1-C12)alkyl, optionally substituted (C2-C1)alkenyl, optionally substituted hetero(C2-C1)alkenyl, optionally substituted (C2-C1)alkynyl, optionally substituted hetero(C2-C1)alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, hydroxyl, halo, imine, amide, nitro, nitroso, nitrile, isocyanate, ester, aldehyde, ketone, carboxyl, thiol, thionyl, and sulfonyl;
- and
- R15 is an optionally substituted (C1-C6)alkyl, an optionally substituted hetero-(C1-C6)alkyl, an optionally substituted (C1-C6)alkenyl, an optionally substituted hetero-(C1-C6)alkenyl, an optionally substituted (C1-C6)alkynyl, or an optionally substituted hetero-(C1-C6)alkynyl, a cycloalkyl, an aryl, and a heterocycle.
2 more elements
A method of promoting a desired tissue morphology and/or physiological state in a higher plant, wherein said desired tissue morphology or physiological state is selected from at least one of:
- shoot growth, grain, seed or fruit yield enhancement, root (radicle) growth retardation, improved fruit set and fruit quality or other desired tissue morphology or physiological state that is promoted by a brassinosteroid, the method comprising applying to the plant an effective amount of a brassinosteroid mimetic of Formula I(a):
- wherein,
- R2, R3, R5, R7, R10-R14 are independently selected from H, D, NH2, —O-alkyl, —O-ether, SH, optionally substituted (C1-C12)alkyl, optionally substituted hetero(C1-C12)alkyl, optionally substituted (C2-C12)alkenyl, optionally substituted hetero(C2-C12)alkenyl, optionally substituted (C2-C12)alkynyl, optionally substituted hetero(C2-C12)alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, hydroxyl, halo, imine, amide, nitro, nitroso, nitrile, isocyanate, ester, aldehyde, ketone, carboxyl, thiol, thionyl, and sulfonyl;
- and
- R15 is an optionally substituted (C1-C6)alkyl, an optionally substituted hetero-(C1-C6)alkyl, an optionally substituted (C2-C6)alkenyl, an optionally substituted hetero-(C2-C6)alkenyl, an optionally substituted (C2-C6)alkynyl, or an optionally substituted hetero-(C1-C6)alkynyl, a cycloalkyl, an aryl, and a heterocycle.
2 more elements
A composition for promoting plant growth comprising a brassinosteroid mimetic as set forth in Formula I(a) in a suitable delivery vehicle, wherein Formula I(a) comprises:
- wherein,
- R2, R3, R5, R7, R10-R14 are independently selected from H, D, NH2, —O-alkyl, —O-ether, SH, optionally substituted (c1-C12)alkyl, optionally substituted hetero(C1-C12)alkyl, optionally substituted (C2-C12)alkenyl, optionally substituted hetero(C2-C12)alkenyl, optionally substituted (C2-C12)alkynyl, optionally substituted hetero(C2-C12)alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, optionally substituted heterocycle, hydroxyl, halo, imine, amide, nitro, nitroso, nitrile, isocyanate, ester, aldehyde, ketone, carboxyl, thiol, thionyl, and sulfonyl;
- and
- R15 is an optionally substituted hetero-(C1-C6)alkyl, an optionally substituted (C2-C6)alkenyl, an optionally substituted hetero-(C2-C6)alkenyl, an optionally substituted (C2-C6)alkynyl, or an optionally substituted hetero-(C2-C6)alkynyl, a cycloalkyl, an aryl, and a heterocycle.
1 more element
Dependencies are inferred from the claim text.