Crystal form of a potassium-competitive acid blocker and preparation method thereof
AssigneeJiangsu Hansoh Pharmaceutical Group Co., Ltd.
InventorsHongwei Tang, Changan Sun, Ruijun Wang, Hengli Yuan
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Abstract
The present invention relates to a crystal form of a potassium-competitive acid blocker, that is, 1-[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrole-3-yl]-N-methyl methylamine fumaric acid salt (which is briefly referred to as a formula I) and a preparation method thereof. An X-ray powder diffraction characteristic peak thereof is shown in FIG. 1. The crystal form that is represented by formula I, provided in the present invention, is stable, reproducible, and is suitable for drug development.
Claims5
A crystal form of 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate, wherein the crystal has a characteristic X-ray powder diffraction spectrum comprising diffraction peaks at diffraction angles (2θ±0.2°):
- 12.30, 13.59, 15.34, 18.67, 20.48, 21.69, 25.23, and 26.92.
A crystal form of 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate, wherein the crystal has an X-ray powder diffraction spectrum as shown in FIG. 1.
Dependencies are inferred from the claim text.