Preparation method of intermediate for oxazolidinone derivative
AssigneeSt Pharm Co., Ltd.
InventorsSeok Hun Woo, YunHee Choi, Hong Jun Kim, Sun Ki Chang, Geun Jho Lim
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Abstract
Disclosed is a method of preparing an intermediate for an oxazolidinone derivative, which enables 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine to be produced at high yield and high purity, thus exhibiting high preparation efficiency under optimal processing conditions and making it suitable for industrial mass production.
Claims17
A method of preparing a compound represented by Chemical Formula 1 below, comprising reacting a compound represented by Chemical Formula 2 below with a methylating agent in presence of a solvent and a base, wherein the solvent is a solvent mixture of a polar aprotic solvent and a hydrocarbon chloride solvent or a polar protic solvent:
Dependencies are inferred from the claim text.