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AssigneeDePuy Synthes Products, Inc.
InventorsRajendra Kasinath, Craig Ernsberger, Stephanie Vass, Steven N. Ginn, Haibo Qu, Weidong Tong
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An orthopedic implant having a metal surface and a hydroxyapatite layer comprising gallium ions therein disposed on at least part of the metal surface is described. The hydroxyapatite layer has an average crystallite size of less than about 75 nm in at least one direction and dissolves for more than 2 hours in vitro. The hydroxyapatite layer is substantially free of carbonate. The coating, which is formed on a sodium titanate surface, has increased shear strength and tensile strength. The coating is formed by a solution deposited hydroxyapatite process under inert conditions. The pH of the solution varies by less than 0.1 pH unit/hour during coating formation.
An orthopedic implant comprising a metal surface and a hydroxyapatite layer disposed on at least part of the metal surface, the hydroxyapatite layer comprising gallium ions therein, wherein the hydroxyapatite layer is crystalline,
An osteoconductive composition comprising hydroxyapatite, the hydroxyapatite comprising gallium ions therein, wherein the hydroxyapatite is crystalline and wherein the hydroxyapatite, when subjected to x-ray diffraction XRD, produces a (002) XRD peak that is shifted by about 0.001° 2θ to about 2° 2θ compared to the (002) XRD peak of crystalline hydroxyapatite without gallium,
Dependencies are inferred from the claim text.