Methods for treating osteoarthritis pain
AssigneeAllergan, Inc.
InventorsCatherine C. Turkel, Guang-Liang Jiang, Ronald E. DeGryse
Life of this patent
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Abstract
Methods for alleviating osteoarthritis-associated symptoms by selecting a treatment-eligible patient and local administration of a clostridial derivative, such as a botulinum toxin, to an osteoarthritis-affected site are disclosed herein.
Claims8
A method for treating or alleviating osteoarthritis (OA)-associated pain in a patient in need thereof, the method comprising identifying an OA patient whose pain has been categorized as nociceptive pain, and locally administering a therapeutically effective amount of a clostridial derivative to an osteoarthritis-affected site of the OA patient whose pain has been categorized as nociceptive pain, thereby treating or alleviating the osteoarthritis-associated pain in the patient,
- wherein the therapeutically effective amount is from about 200 units to about 800 units, wherein the clostridial derivative is onabotulinumtoxinA, and
- wherein the identifying comprises providing the OA patient a plurality of questions relating to characteristics of OA-associated pain that the patient perceives, receiving numerical responses to the questions by the patient, calculating a score based on the numerical responses, comparing the score to a cut-off value to categorize the OA-associated pain;
- and identifying the patient whose pain has been categorized as nociceptive pain.
Dependencies are inferred from the claim text.