Combination preparation including a corticosteroid and exosomes
AssigneeOrthogen AG
InventorsPeter Wehling, Julio Reinecke
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Abstract
The present invention relates to pharmaceutical compositions for a combination therapy with a corticosteroid and exosomes. By means of the combination therapy diseases such as osteoarthritis, arthritis and/or degenerative spinal diseases can be treated.
Claims23
A kit comprising (i) a pharmaceutical composition comprising exosomes in the presence or absence of a cytokine antagonist and/or a growth factor and (ii) a pharmaceutical composition comprising a glucocorticoid in the presence or absence of a cytokine antagonist and/or a growth factor, wherein the exosomes are obtained from blood and the glucocorticoid is one or more selected from the group consisting of, prednisone, prednisolone, cloprednol, deflazacort, fluocortin, triamcinolone, dexamethasone, methylprednisolone, fluprednisolone, clocortolone, clobetasone, alclomethasone, flumethasone, fluoprednidene, fluorandrenolone, betamethasone, beclomethasone, fluocortolone, mometasone, fluticasone, halomethasone, fluocinolone, diflorasone, desoximethasone, fluocinonide, amcinonide, halcinonide, diflucortolone, clobetasol, paramethasone and a salt, ester or prodrug thereof.
Dependencies are inferred from the claim text.