Back to results
US 10,537,584 B2Granted
Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
AssigneeFerring B.V.
InventorsSalah U. Ahmed, Jiaxiang Tsao, Anu Mahashabde, Diane D. Harrison
Life of this patent
Estimating the term…
Abstract
The present invention relates to monolithic intravaginal rings comprising progesterone, methods of making, and uses thereof. The intravaginal rings comprise progesterone, a polysiloxane elastomer, and a pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid.
Claims23
A monolithic intravaginal ring for treating a luteal phase defect in a patient in need thereof, the ring comprising:
- (a) about 10% to about 30% by weight of progesterone;
- (b) about 60% to about 80% by weight of polysiloxane elastomer;
- and
- (c) about 1% to about 8% by weight of a pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid or pharmaceutically acceptable oil,
- wherein the progesterone is homogeneously dispersed in the elastomer.
2 more elements
A monolithic intravaginal ring for treating a luteal phase defect in a patient in need thereof, wherein the intravaginal ring comprises:
- (a) about 15% to about 25% by weight of the progesterone;
- (b) about 70% to about 80% by weight of a dimethylpolysiloxane elastomer;
- and
- (c) about 1% to about 8% by weight of mineral oil,
- wherein the progesterone is homogeneously dispersed in the elastomer.
2 more elements
Dependencies are inferred from the claim text.