Methods for treating ocular disease using inhibitors of CSF-1R
AssigneeNovartis AG
InventorsChristopher Adams, Muneto Mogi, Stephen Hedrick Poor, Timothy Michael Ramsey, Henry Wu, Qin Zhang
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Abstract
The present invention provides in one aspect methods for treating ocular diseases by administering pharmaceutical compositions comprising an inhibitor of colony stimulating factor-1 (CSF-1) receptors. In another aspect, the present invention provides pharmaceutical compositions for treating ocular diseases, the compositions comprising at least one inhibitor of CSF-1R. The inhibitor can also be a selective inhibitor of CSF-1R in certain embodiments.
Claims19
A method of treating an ocular disease or disorder that is mediated by CSF-1R comprising:
- administering to a subject in need thereof an effective amount of Compound (I):
- as a non-salt or a pharmaceutically acceptable salt thereof.
A method of treating diabetic retinopathy, diabetic macular edema, or age-related macular degeneration, in a mammalian subject suffering therefrom, said method comprising administering to the subject an effective amount of Compound (I):
- as a non-salt or a pharmaceutically acceptable salt thereof in a pharmaceutical composition.
Dependencies are inferred from the claim text.