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US 10,537,551 B2Granted
Tesofensine and beta blocker combination formulations
AssigneeSaniona A/S
InventorsPeter G. Nielsen, Mikael S. Thomsen, Bent Højgaard
Life of this patent
Estimating the term…
Abstract
The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or carvedilol, or a pharmaceutically acceptable salt thereof. The invention further relates to use of the controlled release formulation in a method of treatment of diabetes, obesity, or an obesity associated disorder.
Claims21
A pharmaceutical composition comprising
- a. a first composition comprising an extended release (ER) composition of a beta blocker or a pharmaceutically acceptable salt thereof,
- b. a second composition comprising tesofensine or a pharmaceutically acceptable salt thereof, and
- c. a third composition comprising an immediate release (IR) composition of a beta blocker or a pharmaceutically acceptable salt thereof;
- wherein the first composition is included in a tablet core coated with a coating comprising the second composition and the third composition.
1 more element
A pharmaceutical composition comprising
- a. a first composition comprising an extended release (ER) composition of metoprolol or a pharmaceutically acceptable salt thereof,
- b. a second composition comprising tesofensine or a pharmaceutically acceptable salt thereof, and
- c. a third composition comprising an immediate release (IR) composition of a metoprolol or a pharmaceutically acceptable salt thereof;
- wherein the first composition is included in a tablet core coated with a coating comprising the second composition and the third composition.
1 more element
Dependencies are inferred from the claim text.