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US 10,537,541 B2Granted
Treatment of focal segmental glomerular sclerosis (FSGS) using therapeutically effective oral doses of 10-nitro-9(E)-octadec-9-enoic acid
AssigneeComplexa, Inc.
InventorDiane Jorkasky
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Abstract
Various embodiments of this invention are directed to pharmaceutical compositions and methods for treating diseases, including focal segmental glomerulosclerosis or pulmonary arterial hypertension. The compositions of such embodiments include activated fatty acids such as alkyl substituted fatty acids, keto fatty acids and nitro fatty acids. The methods of various embodiments include administering an effective amount of 10-nitro-9(E)-octadec-9-enoic acid to treat such diseases.
Claims6
A method of treating focal segmental glomerular sclerosis (FSGS), comprising:
- administering to a human patient with FSGS an oral daily dose of 10-nitro-9(E)-octadec-9-enoic acid in an amount greater than 25 mg and less than 450 mg per day.
Dependencies are inferred from the claim text.