Chemical ablation and method of treatment for various diseases
AssigneeNeurotronic, Inc.
InventorLixiao Wang
Life of this patent
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Abstract
Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, nonalcoholic fatty liver disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
Claims25
A method for treating a disease, the method comprising:
- inserting a balloon delivery catheter into a body lumen, the balloon delivery catheter comprising a distal balloon at a distal portion of the balloon delivery catheter, wherein the distal balloon is the most distal balloon of the balloon delivery catheter, a proximal balloon closer to a proximal portion of the balloon delivery catheter than the distal balloon, wherein the proximal balloon is the most proximal balloon of the balloon delivery catheter, and a middle section that extends from the proximal balloon to the distal balloon, wherein in an expanded state the proximal balloon and the distal balloon have a larger maximum diameter than a maximum diameter of the middle section;
- inflating the balloon delivery catheter to form an uninterrupted treatment window in the body lumen extending from the proximal balloon to the distal balloon;
- infusing a formulation from the balloon delivery catheter to a tissue in the body lumen, wherein the formulation delivered to the tissue is effective to injure or damage nerves or nerve endings in the tissue to relieve disease symptoms;
- the infusion comprising:
- infusing the formulation into the treatment window to contact the formulation with the tissue, wherein the tissue is tissue in the body lumen in the treatment window, or
- infusing the formulation from a distal tip of the balloon delivery catheter into the body lumen distal to the distal balloon to contact the formulation with the tissue wherein the tissue is tissue in the body lumen distal to the distal balloon, or a combination thereof,
- flushing the body lumen with saline solution to dilute the formulation;
- deflating the balloon delivery catheter;
- removing at least some of the formulation from the tissue prior to the flushing;
- and
- withdrawing the delivery catheter from the body lumen.
Dependencies are inferred from the claim text.