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US 10,537,308 B2Granted
Catheter for prevention of stroke and method of use
OwnerMichael Zhadkevichinventor
Life of this patent
Estimating the term…
Abstract
A catheter for prevention of stroke by diverting and filtering the blood flow to carotid and vertebral arteries is provided. The catheter includes at least one balloon with an outer mesh cover that expands upon the balloon inflation and stays expanded after the balloon is deflated. The inflation of the balloon in the aortic arch or head vessels provides the deflection of embolic particles from the cerebral circulation and expands the outer mesh that provides for filtering and deflection of cerebral emboli after the balloon is deflated. An associated method of prevention of cerebral emboli and embolic stroke is provided.
Claims26
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery, wherein the occluding balloon is coaxial with the shaft;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded and maintains the expanded configuration when the occluding balloon is deflated, wherein the filtering mesh is coaxial with the shaft, wherein expansion of the occluding balloon causes expansion of the filtering mesh;
- wherein blood flows through pores of the filtering mesh when the occluding balloon is deflated, wherein blood flows through the pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- wherein the blood does not flow through the pores of the filtering mesh that are formed by the portions of the filtering mesh that are in contact with the occluding balloon when, the occluding balloon is fully inflated;
- wherein the filtering mesh is carried by the shaft such that the pores of the filtering mesh are located proximal to the occluding balloon extend across the occluding balloon and are located distal to the occluding balloon.
4 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded and maintains the expanded configuration when the occluding balloon is deflated;
- wherein blood flows through pores of the filtering mesh when the occluding balloon is deflated, wherein blood flows through the pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- wherein the blood does not flow through the pores of the filtering mesh that are formed by the portions of the filtering mesh that are in contact with the occluding balloon when the occluding balloon is fully inflated;
- wherein the occluding balloon is a proximal occluding balloon and further comprising a distal occluding balloon that is surrounded by the filtering mesh;
- wherein the proximal occluding balloon is inflated to occlude blood flow and expand the filtering mesh to filter blood flow to the right carotid artery or the left carotid artery;
- wherein the distal occluding balloon is inflated to occlude blood flow and to expand the filtering mesh to filter blood flow to the other one of the right carotid artery or the left carotid artery not occluded and filtered by the proximal occluding balloon;
- wherein both the proximal and distal occluding balloons when deflated allow blood flow through the filtering mesh and to the right and left carotid arteries, wherein when the proximal and distal occluding balloons are fully inflated blood flow through the pores of the filtering mesh is prevented adjacent the proximal and distal occluding balloons;
- wherein the shaft has a segment that is located between the proximal occluding balloon and the distal occluding balloon.
8 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded and maintains the expanded configuration when the occluding balloon is deflated;
- wherein blood flows through pores of the filtering mesh when the occluding balloon is deflated, wherein blood flows through the pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- wherein the blood does not flow through the pores of the filtering mesh that are formed by the portions of the filtering mesh that are in contact with the occluding balloon when the occluding balloon is fully inflated;
- wherein the occluding balloon is a proximal occluding balloon and further comprising a distal occluding balloon that is surrounded by the filtering mesh;
- wherein the proximal occluding balloon is inflated to occlude blood flow and expand the filtering mesh to filter blood flow to the right carotid artery or the left carotid artery;
- wherein the distal occluding balloon is inflated to occlude blood flow and to expand the filtering mesh to filter blood flow to the other one of the right carotid artery or the left carotid artery not occluded and filtered by the proximal occluding balloon;
- wherein both the proximal and distal occluding balloons when deflated allow blood flow through the filtering mesh and to the right and left carotid arteries, wherein when the proximal and distal occluding balloons are fully inflated blood flow through the pores of the filtering mesh is prevented adjacent the proximal and distal occluding balloons;
- wherein the shaft has a segment that is located between the proximal occluding balloon and the distal occluding balloon;
- wherein the shaft has an intermediate pressure measurement and blood aspiration channel that extends from an intermediate pressure measurement and blood aspiration channel opening of the shaft located proximal to the proximal occluding balloon, wherein the intermediate pressure measurement and blood aspiration channel extends to an intermediate pressure measurement and aspiration port located at the proximal end of the shaft;
- and wherein the intermediate pressure measurement and blood aspiration channel opening is located inside the filtering mesh and aspirates trapped particles from the space inside the filtering mesh when the filtering mesh is in the expanded configuration.
10 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded and maintains the expanded configuration when the occluding balloon is deflated;
- wherein blood flows through pores of the filtering mesh when the occluding balloon is deflated, wherein blood flows through the pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- wherein the blood does not flow through the pores of the filtering mesh that are formed by the portions of the filtering mesh that are in contact with the occluding balloon when the occluding balloon is fully inflated;
- wherein the shaft has an intermediate pressure measurement and blood aspiration channel that extends from an intermediate pressure measurement and blood aspiration channel opening of the shaft located proximal to the occluding balloon, wherein the intermediate pressure measurement and blood aspiration channel extends to an intermediate pressure measurement and aspiration port located at the proximal end of the shaft;
- and wherein the intermediate pressure measurement and blood aspiration channel opening is located outside of the filtering mesh when the filtering mesh is in the expanded configuration;
- wherein the filtering mesh is carried by the shaft such that the pores of the filtering mesh are located proximal to the occluding balloon extend across the occluding balloon and are located distal to the occluding balloon.
6 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid, artery;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded and maintains the expanded configuration when the occluding balloon is deflated;
- wherein blood flows through pores of the filtering mesh when the occluding balloon is deflated, wherein blood flows through the pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- wherein the blood does not flow through the pores of the filtering mesh that are formed by the portions of the filtering mesh that, are in contact with the occluding balloon when the occluding balloon is fully inflated;
- ultrasound Doppler probes mounted along the shaft, wherein the probes detect:
- real time embolic signals,
- paths of emboli,
- intensity and direction of propagation of the emboli in relation to an aortic arch and head vessels,
- blood velocity and B-mode images of an aorta, innominate artery,
- and left and right carotid arteries,
- an alarm system that activates a pressure supply to the occluding balloon to cause inflation and the filtering mesh expansion when embolic signals, complete or partial occlusion of the carotid arteries, or increased or decreased systolic velocity and abnormal flow patterns are detected by the ultrasound probes;
- wherein the alarm system deflates the occluding balloon when the occluding balloon remains inflated for a cut-off period of time, and wherein the alarm system has a manual override to prevent inflation and deflation by the alarm system.
11 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end, wherein the shaft has a blood aspiration channel that extends from a blood aspiration channel opening of the shaft, wherein particles are aspirated through the blood aspiration channel opening of the shaft;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery, wherein the occluding balloon engages the shaft;
- and
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated, wherein the filtering mesh engages the shaft at a location proximal to the occluding balloon and the blood aspiration channel opening, and wherein the filtering mesh engages the shaft at a location distal to the occluding balloon and the blood aspiration channel opening;
- wherein the blood aspiration channel opening is configured for aspirating emboli from inside of the filtering mesh.
2 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end, wherein the shaft has a blood aspiration channel that extends from a blood aspiration channel opening of the shaft, wherein particles are aspirated through the blood aspiration channel opening of the shaft;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery, wherein the occluding balloon engages the shaft;
- and
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated, wherein the filtering mesh, engages the shaft at a location proximal to the occluding balloon and wherein the filtering mesh engages the shaft at a location distal to the occluding balloon;
- wherein the blood aspiration channel is an intermediate pressure measurement and blood aspiration channel, and wherein the blood aspiration channel opening is an intermediate pressure measurement and blood aspiration channel opening;
- wherein the shaft has an occluding balloon channel that extends from the occluding balloon to an occluding balloon inflation port located at the proximal end of the shaft, wherein the shaft has an end pressure measurement-aspiration channel that extends from a distal tip opening of the shaft located at the distal end of the shaft to an end pressure measurement-aspiration port located at the proximal end of the shaft,
- wherein the intermediate pressure measurement and blood aspiration channel opening is located proximal to both the occluding balloon and the distal tip opening to an intermediate pressure measurement and blood aspiration port located at the proximal end of the shaft, and
- wherein at least one of the intermediate pressure measurement and blood aspiration channel opening or the distal tip opening opens into the space between the occluding balloon and the filtering mesh and aspirates emboli from the space inside of the filtering mesh and from the blood passing through.
5 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end, wherein the shaft has a blood aspiration channel that extends from a blood aspiration channel opening of the shaft, wherein particles are aspirated through the blood aspiration channel opening of the shaft;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- and
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated;
- wherein the occluding balloon has a proximal portion and a distal portion in which the proximal portion is larger than the distal portion, wherein the proximal portion is located within an innominate artery of the patient and completely occludes blood flow to the right carotid artery and to a right subclavian artery of the patient when inflated, wherein the distal portion is located within the left carotid artery and when inflated completely occludes blood flow to the left carotid artery;
- wherein the blood is allowed to flow through the pores when the balloon is deflated, but not allowed to flow through the pores when the balloon is completely inflated, and wherein partial inflation of the occluding balloon leads to a partial restriction of the blood flow through the filtering mesh.
3 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end, wherein the shaft has a blood aspiration channel that extends from a blood aspiration channel opening of the shaft, wherein particles are aspirated through the blood aspiration channel opening of the shaft;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- and
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated;
- wherein the occluding balloon has a first occluding balloon and a second occluding balloon, wherein the first occluding balloon is located within a right subclavian artery, but not within an innominate or right carotid artery,
- wherein the second occluding balloon is located within the left subclavian artery, but not within the left carotid artery,
- wherein the filtering mesh covering both occluding balloons is expanded and stretched between the two occluding balloons, when the two occluding balloons cover an area of an aortic arch containing orifices of the innominate, carotid and subclavian arteries,
- wherein the filtering mesh stays expanded after the occluding balloons are deflated,
- wherein the filtering mesh collapses around the shaft after the two occluding balloons are deflated, and
- wherein the process of collapsing the filtering mesh around the shaft is performed by a mechanism selected from the group consisting of spontaneous recoil, aspiration, retraction process, torqueing process, or rotational process.
7 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery;
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated;
- and
- an adjustment mechanism that adjusts pore sizes of the pores of the filtering mesh.
2 more elements
A catheter for preventing stroke, comprising:
- a shaft that has a proximal end and a distal end;
- an occluding balloon carried by the shaft, wherein the occluding balloon is inflated to occlude blood flow to at least one of the right carotid artery and the left carotid artery, wherein the occluding balloon engages the shaft;
- and
- a filtering mesh that assumes an expanded configuration when the occluding balloon is expanded, wherein blood flows through pores of the filtering mesh when the occluding balloon is partially inflated, wherein the filtering mesh engages the shaft at a location proximal to the occluding balloon and wherein the filtering mesh engages the shaft at a location distal to the occluding balloon;
- wherein the filtering mesh is carried by the shaft such that the pores of the filtering mesh are located proximal to the occluding balloon extend across the occluding balloon and are located distal to the occluding balloon;
- wherein the mesh has an area configured for facing arterial inflow of blood, and wherein the mesh has an area configured for facing arterial outflow of blood that is located opposite in a radial direction from the area configured for facing arterial inflow of blood, wherein the pares in the area of the mesh configured for facing arterial inflow of blood are larger in size than the pores in the area of the mesh configured for facing arterial outflow of blood.
3 more elements
Dependencies are inferred from the claim text.