Attenuation map reconstruction from TOF PET data
AssigneeRensselaer Polytechnic Institute
InventorsGe Wang, Qingsong Yang, Wenxiang Cong
Life of this patent
Estimating the term…
Abstract
Systems and methods for determining an attenuation sinogram for a time-of-flight (TOF) positron emission tomography (PET) scan using only TOF PET data, and including use of the total amount of tracer provided to the subject of the TOF PET scan, are provided. The total amount of injected tracer can be used to determine the otherwise unknown constant shift present when an attenuation sinogram is estimated using the gradient of the attenuation sinogram. The attenuation sinogram can therefore be accurately and stably determined without any additional knowledge on the attenuation sinogram or map.
Claims20
A system for performing a time-of-flight (TOF) positron emission tomography (PET) scan, the system comprising:
- a PET scanner configured to perform TOF PET scanning;
- at least one processor;
- and
- a machine-readable medium, in operable communication with the PET scanner and the at least one processor, having machine-executable instructions stored thereon that, when executed by the at least one processor, perform a method, the method comprising:
- obtaining an initial estimated attenuation singoram of a TOF PET scan, of the PET scanner, that has an unknown constant shift;
- determining the constant shift of the initial estimated attenuation singoram using the total amount of tracer provided to the subject of the TOF PET scan, wherein
- determining the constant shift is done without using any further information other than TOF PET scan data;
- and
- determining the attenuation sinogram for the TOF PET scan using the determined constant shift and the initial estimated attenuation sinogram.
A system for determining an attenuation sinogram for a time-of-flight (TOF) positron emission tomography (PET) scan, the system comprising:
- at least one processor;
- and
- a machine-readable medium, in operable communication with the at least one processor, having machine-executable instructions stored thereon that, when executed by the at least one processor, perform a method, the method comprising:
- obtaining an initial estimated attenuation singoram of a TOF PET scan that has an unknown constant shift;
- determining the constant shift of the initial estimated attenuation singoram using the total amount of tracer provided to the subject of the TOF PET scan, wherein
- determining the constant shift is done without using any further information other than TOF PET scan data;
- and
- determining the attenuation sinogram for the TOF PET scan using the determined constant shift and the initial estimated attenuation sinogram.
A method for performing a time-of-flight (TOF) positron emission tomography (PET) scan on a subject, the method comprising:
- providing a tracer to the subject to be scanned;
- scanning the subject in a PET scanner configured to perform TOF PET scanning;
- and
- determining an attenuation sinogram for the TOF PET scan,
- wherein determining the attenuation sinogram for the TOF PET scan comprises:
- obtaining an initial estimated attenuation singoram of the TOF PET scan, that has an unknown constant shift;
- determining the constant shift of the initial estimated attenuation singoram using the total amount of tracer provided to the subject of the TOF PET scan, wherein
- determining the constant shift is done without using any further information other than TOF PET scan data;
- and
- determining the attenuation sinogram for the TOF PET scan using the determined constant shift and the initial estimated attenuation sinogram.
Dependencies are inferred from the claim text.