Systems and methods for generating nitric oxide
AssigneeThird Pole, Inc.
InventorsDavid G. Zapol, Gregory W. Hall, Wolfgang Scholz
Life of this patent
Estimating the term…
Abstract
Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
Claims24
A nitric oxide generation system, comprising:
- one or more plasma chambers configured to ionize a reactant gas to generate a plasma for producing a product gas containing nitric oxide (NO) using a flow of the reactant gas through the one or more plasma chambers;
- a controller configured to regulate the amount of nitric oxide in the product gas in the one or more plasma chambers using one or more parameters as input to a control algorithm, at least one of the one or more parameters being related to a target concentration of NO in a combination of the product gas and a medical gas into which the product gas flows;
- a flow controller configured to provide a controlled variable flow of the reactant gas into the one or more plasma chambers based on a measurement associated with the medical gas;
- and
- one or more scrubber paths configured to remove NO2 from the product gas generated by the one or more plasma chambers,
- wherein the target concentration of NO in the combination of the product gas and the medical gas is a variable target concentration,
- wherein the measurement associated with the medical gas is the flow rate of the medical gas such that the flow of the reactant gas through the one or more plasma chambers is proportional to the flow rate of the medical gas.
A nitric oxide generation system, comprising:
- one or more plasma chambers configured to ionize a reactant gas to generate a plasma for producing a product gas containing nitric oxide (NO) using a flow of the reactant gas through the one or more plasma chambers;
- a controller configured to regulate the amount of nitric oxide in the product gas in the one or more plasma chambers using one or more parameters as input to a control algorithm, at least one of the one or more parameters being related to at least one of a target concentration of NO in a combination of the product gas and a medical gas into which the product gas flows and a gas flow rate measurement of at least one of the medical gas and the reactant gas;
- and
- a flow controller configured to provide a controlled variable flow of the reactant gas based on a measurement associated with a medical gas into which the product gas flows,
- wherein the gas flow rate measurement of the medical gas is the flow rate of the medical gas such that the air flow of the reactant gas through the one or more plasma chambers is proportional to the flow rate of the medical gas.
Dependencies are inferred from the claim text.