Method for measuring tear constituents in a tear sample
AssigneeDiagnostear, Ltd.
InventorsAmos Sommer, Ouriel Faktor, Eran Eilat
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Abstract
The present invention provides a method, wherein the method classifies a subject as suffering from dry eye, the method consisting of: a. obtaining demographic data, consisting of the age and gender of the subject; b. obtaining a tear sample from the patient, and determining the level of human serum albumin; c. from the determined level of human serum albumin, assigning a score for the determined amount of human serum albumin; and d. from the assigned score, calculating a cutoff probability score, according to the following equation: wherein the subject has dry eye, if the calculated cutoff probability score is from 50% to 60%. exp ( - 0.6491 - 1.1142 * Albumin ) 1 + exp ( - 0.6491 - 1.1142 * Albumin )
Claims5
A method, wherein the method classifies a subject as suffering from dry eye, the method consisting of:
- a. obtaining demographic data, consisting of the age and gender of the subject;
- b. obtaining a tear sample from the patient, and determining the level of human serum albumin, lactoferrin, and lysozyme;
- c. from the determined level of human serum albumin, lactoferrin, and lysozyme, assigning a score for the determined amount of human serum albumin, lactoferrin, and lysozyme;
- and
- d. from the assigned score, calculating a cutoff probability score, according to the following equation:
- exp
- (
- -
- 5.7198
- -
- 3.9059
- *
- Albumin
- -
- 0.7375
- *
- Lysozyme
- -
- 2.7929
- *
- Lactoferrin
- +
- 0.1507
- *
- Age
-
- (
- yrs
- )
- +
- 1.2206
- *
- (
- -
- 1
-
-
- if
-
-
- male
- )
- +
- 7.1682
- *
- Albumin
- *
- Lactoferrin
- +
- 4.4090
- *
- Albumin
- *
- Lysozyme
- -
- 10.7566
- *
- Lysozyme
- *
- Lactoferrin
- )
- 1
- +
- exp
- (
- -
- 5.7198
- -
- 3.9059
- *
- Albumin
- -
- 0.7375
- *
- Lysozyme
- -
- 2.7929
- *
- Lactoferrin
- +
- 0.1507
- *
- Age
-
- (
- yrs
- )
- +
- 1.2206
- *
- (
- -
- 1
-
-
- if
-
-
- male
- )
- +
- 7.1682
- *
- Albumin
- *
- Lactoferrin
- +
- 4.4090
- *
- Albumin
- *
- Lysozyme
- -
- 10.7566
- *
- Lysozyme
- *
- Lactoferrin
- )
- wherein the subject has dry eye, if the calculated cutoff probability score is from 50% to 60%.
Dependencies are inferred from the claim text.