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US 10,526,296 B2Granted
Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light
AssigneeJohnson & Johnson Vision Care, Inc.
InventorsShivkumar Mahadevan, Leilani K. Sonoda, Dola Sinha, Patricia Martin
Life of this patent
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Abstract
Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl naphthotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl naphthotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.
Claims15
A compound of formula I:
- wherein:
- R1 at each occurrence is independently H, halo, C1-C6 alkyl, C3-C12 cycloalkyl, aryl, or aryl-C1-C6-alkyl;
- at least one R2 is a group of formula Rg-L, wherein Rg is a polymerizable group and L is a linking group, and the remaining R2 are independently at each occurrence Rg-L, H, C1-C6 alkyl, C3-C12 cycloalkyl, aryl, or aryl-C1-C6-alkyl, wherein L at each occurrence is independently —[CH2]m—Y—[CH2]n—, wherein m is a number from 1 to 6, n is a number from 1 to 6, Y is O, S, C(═O)O, NR3, or C(═O)NR3, and R3 is H or C1-C4 alkyl;
- and
- wherein each alkyl, cycloalkyl, and aryl group is unsubstituted or substituted.
2 more elements
A compound that is:
- 3-(4-Hydroxy-3-(2H-naphtho[2,3-d][1,2,3]triazol-2-yl)phenyl)propanoic acid or triethylamine 3-(4-hydroxy-3-(2H-naphtho[2,3-d] [1,2,3]triazol-2-yl)phenyl)propanoate.
Dependencies are inferred from the claim text.