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US 10,525,020 B2Granted
Metabolic markers of attention deficit hyperactivity disorder
AssigneeLaboratory Corporation of America Holdings
InventorsUte Geigenmuller, Doris Damian, Maciej Pacula, Mark A. DePristo
Life of this patent
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Abstract
Disclosed herein are methods for treating subjects having ADHD identifiable by levels of 3-IS in blood.
Claims12
A method of measuring an increase in 3-Indoxyl Sulfate (3-IS) in a human subject suspected of having or observed to have atypical development for determination of the presence of attention deficit hyperactivity disorder (ADHD), the method comprising:
- obtaining a blood sample from the subject;
- measuring a 3-IS level in the sample by mass spectrometry;
- and determining that the subject has ADHD when the measured 3 -IS level in the blood sample is higher than a reference level, wherein the reference level is a level of 3-IS derived from subjects who do not have ADHD.
Dependencies are inferred from the claim text.