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AssigneeThe University Court of the University of Edinburgh
InventorsMark Bradley, Annamaria Helena Lilienkampf, Nikolaos Avlonitis, Marc Vendrell Escobar, Neil Alexander McDonald, Christopher Haslett, Kanwaldeep Dhaliwal, Timothy Simon Walsh
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A probe for detecting bacteria and/or fungi in vitro and in vivo is provided, the probe having a core and a plurality of probe elements; each probe element within the plurality of probe elements extending from the core and having a fluorophore and a binding moiety, wherein the binding moiety is a bacteria binding moiety and selectively binds to bacteria and/or to fungi and not to animal cells. Methods of use of the probe and kits comprising the probe are also provided.
A probe comprising a core and a plurality of probe elements, each probe element within the plurality of probe elements extending from the core and comprising a fluorophore and a binding moiety, wherein the binding moiety is a bacteria binding moiety and selectively binds to at least some bacteria, and does not bind to animal cells, or wherein the binding moiety is a fungi binding moiety, or wherein the binding moiety selectively binds to at least some bacteria and to at least some fungi, and not bind to animal cells, wherein the probe has one of the following structures:
Dependencies are inferred from the claim text.