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US 10,519,465 B2Granted
Tissue selective transgene expression
AssigneeEncoded Therapeutics, Inc.
InventorsStephanie Tagliatela, Andrew Young, Szu-Ying Chen, Kartik Ramamoorthi, David Oberkofler
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Abstract
Provided herein are compositions and methods for selective expression of a transgene. Compositions and methods for selective expression of a transgene comprise one or more human regulatory elements, which, when operably linked to a transgene, can facilitate selective expression of a transgene (e.g., cell-type selective expression) in a target cell as compared to at least one or more non-target cells.
Claims13
A nucleic acid cassette comprising a regulatory element comprising SEQ ID NO:
- 30 operably linked to a transgene.
Dependencies are inferred from the claim text.