Biologic sample collection devices and methods of production and use thereof

A method for collecting a biologic sample, the method comprising the steps of:

• contacting a biologic sample collection device comprising soluble and hydrophilic polycaprolactone coupled to a carrier, wherein at least a portion of the polycaprolactone solubilizes when exposed to a nucleic acid extraction reagent, with a biologic sample such that the biologic sample is reversibly adhered to the polycaprolactone;
• contacting the biologic sample collection device and the biologic sample with at least one nucleic acid extraction reagent comprising a ketone or an ester, and an emulsifying agent, under conditions such that the polycaprolactone is solubilized and the sample is separated from the biologic sample collection device;
• and
• collecting the separated sample.