Nicotinamide phosphoribosyltransferase (NAMPT) mutant and use thereof
AssigneeBontac Bio-Engineering (Shenzhen) Co., Ltd
InventorsRongzhao Fu, Qi Zhang
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Abstract
The present invention discloses a Nicotinamide phosphoribosyltransferase (nampt) mutant and use thereof. The present invention relates to a nicotinamide phosphoribosyltransferase (Nampt) mutant artificially obtained through genic site-directed mutation. An object of the present invention is to provide a Nampt mutant having a catalytic activity higher than that of a conventional wild type parent, wherein the enzymatic activity of the Nampt mutant provided in the present invention is 1.2-6.9 times of the enzymatic activity of the parent.
Claims17
A nicotinamide phosphoribosyltransferase (Nampt) mutant, wherein the Nampt mutant is a protein having an amino acid sequence selected from the group consisting of SEQ ID NO:
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Dependencies are inferred from the claim text.