Antimicrobial coatings
AssigneeAgency for Science, Technology and Research
InventorsYugen Zhang, Yuan Yuan
Life of this patent
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Abstract
A coating comprising a metal-organic framework, wherein the metal-organic framework having a zeolitic structure comprising at least one multivalent metal species and at least one organic ligand (such as zeolitic imidazolate framework (ZIF)). Said coating has a topography comprising an array of projections, and each projection having at least one tapered distal end. There is also provided a method of coating substrates with the disclosed coating and use of said coating as a disinfectant, an antiseptic, or an antibiotic. Such use is possible because the tapered distal end of the disclosed zeolitic structure exerting higher pressure on any microbial cell that comes into contact with the disclosed coating, thereby piercing through the cell membrane more easily, causing cell deformation and lysis.
Claims20
A method of killing or inhibiting the growth of a microorganism, said method comprising:
- contacting said microorganism with a coating composition, wherein the coating composition comprises a topography having an array of projections formed of a zeolitic imidazolate framework (ZIF),
- wherein the ZIF comprises at least one multivalent metal species and at least one organic ligand,
- wherein each projection has at least one tapered distal end, and
- wherein said projections possess a height greater than or equal to 1 micron.
The method of preparing a disinfectant, antiseptic or an antibiotic comprising coating a surface of a substrate with a coating composition, comprising a topography having an array of projections formed of a zeolitic imidazolate framework (ZIF), wherein the ZIF comprises at least one multivalent metal species and at least one organic ligand, wherein each projection has at least one tapered distal end, and wherein said projections possess a height greater than or equal to 1 micron.
Dependencies are inferred from the claim text.