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US 10,519,278 B2Granted
Methods of making polypeptides
AssigneeBoard of Supervisors of Louisiana State University
InventorsDonghui Zhang, Jinbao Cao, Brandon Chan, David Siefker
Life of this patent
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Abstract
Various embodiments disclosed relate to a method of forming a polypeptide. The method includes contacting a first amino acid-derived N-thiocarboxyanhydrosulfide monomer as a crystalline solid with a polymerization initiator (e.g., in an alkane suspension) to give a polypeptide product. The method further includes contacting the polypeptide product with a second amino acid-derived N-thiocarboxyanhydrosulfide monomer in an alkane suspension.
Claims14
A method of forming a polypeptide comprising:
- contacting an amino acid-derived N-thiocarboxyanhydrosulfide monomer with a polymerization initiator in a nonpolar solvent to give a polypeptide.
Dependencies are inferred from the claim text.