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US 10,519,243 B2Granted
Anti-CD40 antibodies
AssigneeAbbVie Biotherapeutics Inc.
InventorsDiane Sau Mun Cohen, Diane Hollenbaugh, Shiming Ye
Life of this patent
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Abstract
The present disclosure provides novel anti-CD40 antibodies, compositions including the new antibodies, nucleic acids encoding the antibodies, and methods of making and using the same.
Claims9
An anti-CD40 antibody or binding fragment which comprises (i) a VH chain comprising three CDRs;
- and (ii) a VL chain comprising three CDRs, wherein:
- VH CDR#1 is
- (SEQ ID NO:
- 6)
- GYTFTSYWMH,
- VH CDR#2 is
- (SEQ ID NO:
- 16)
- NIDPSNGETHYNQKFKD,
- VH CDR#3 is
- (SEQ ID NO:
- 36)
- ERIYYSGSTYDGYFDV, or
- VL CDR#1 is
- (SEQ ID NO:
- 56)
- SASSSLSYMH, or
- VL CDR#2 is
- (SEQ ID NO:
- 66)
- DTSKLAS, or
- VL CDR#3 is
- (SEQ ID NO:
- 86)
- QQWSSNPWT, or
22 more elements
Dependencies are inferred from the claim text.