1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their bacterial infections
AssigneeWockhardt Limited
InventorsVijaykumar Jagdishwar Patil, Ravikumar Tadiparthi, Bharat Dond, Amol Kale, Loganathan Velupillai, Deepak Dekhane, Satish Shrimant Birajdar, Mohammad Usman Shaikh, Sushilkumar Maurya, Piyush Ambalal Patel, Prasad Dixit, Mangesh Pawar, Mahesh Vithalbhai Patel, Sachin Bhagwat
Life of this patent
Estimating the term…
Abstract
Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.
Claims9
A method for treating bacterial infection, comprising orally administering to a subject in need thereof a pharmaceutically effective amount of (a) at least one antibacterial agent selected from the group consisting of cefpodoxime, ceftibuten, cefuroxime, cefixime and pharmaceutically acceptable salts thereof;
- and (b) at least one compound selected from a group consisting of:
- and a stereoisomer;
- and a pharmaceutically acceptable salt thereof.
A method for treating bacterial infection, comprising orally administering to a subject in need thereof a pharmaceutical composition comprising:
- (a) at least one antibacterial agent selected from the group consisting of cefpodoxime, ceftibuten, cefuroxime, cefixime and pharmaceutically acceptable salts thereof;
- (b) one or more pharmaceutically acceptable excipients;
- and (c) at least one compound selected from a group consisting of:
- and a stereoisomer;
- and a pharmaceutically acceptable salt thereof.
A method for increasing antibacterial effectiveness of an antibacterial agent selected from the group consisting of cefpodoxime, ceftibuten, cefuroxime, cefixime and pharmaceutically acceptable salts thereof, comprising co-administering to a subject in need thereof the antibacterial agent with a pharmaceutically effective amount of at least one compound selected from a group consisting of:
- and a stereoisomer;
- and a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.