Modulators of SOCE, compositions, and uses thereof
AssigneeUniversita Degli Studi Del Piemonte Orientale
InventorsTracey Pirali, Armando A. Genazzani, Beatrice Riva
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AssigneeUniversita Degli Studi Del Piemonte Orientale
InventorsTracey Pirali, Armando A. Genazzani, Beatrice Riva
Estimating the term…
Compounds of Formula (I) able to modulate Store Operated Calcium Entry (SOCE). The disclosure also relates to the use of compounds of formula (I) for treatment of pathological conditions in which SOCE modulation might be beneficial, such as neglecting disorders linked to loss- or gain-of-function STIM1/Orai1 mutations, allergic disorders, pain, inflammatory diseases, autoimmune diseases or disorders, cancer and other proliferative diseases, neurodegenerative disorders, myelodysplastic syndromes, haematological diseases, cardiovascular diseases, degenerative diseases of the musculoskeletal system, liver diseases and disorders, kidney diseases, type I diabetes, graft rejection, graft-versus-host disease, allogeneic or xenogeneic transplantation, thyroiditis and viral infections.
A compound of formula (I)
Dependencies are inferred from the claim text.