Method for producing heteroaromatic sulfonamide compound

A method for producing a sulfonamide compound of the general formula (4):

• wherein
• R1 is a pyridyl group which is unsubstituted or substituted;
• and
• R2 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, an aryl group, a heteroaryl group, an aralkyl group or a heteroarylalkyl group, which is unsubstituted or substituted,
• comprising the steps of:
• (A) reacting a sulfonic acid compound of the general formula (2):
• wherein
• R1 is as defined above,
• with a sulfonylating agent selected from the group consisting of a perfluoroalkyl sulfonic acid anhydride or a perfluoroalkyl sulfonic acid halide to yield a mixed sulfonic acid anhydride of the general formula (1):
• wherein
• R1 is as defined above and R3 is a perfluoroalkyl group;
• and
• (B) subsequently conducting a reaction by adding an amine compound of the general formula (3);
• H2N—R2 (3)
• wherein
• R2 is as defined above,
• to the reaction solution obtained in the step (A).