Devices for separation of particulates, associated methods and systems

A system comprising:

• (a) a separation device for separating particulates dispersed within a base fluid and having a relative density difference compared to the base fluid, comprising:
• a fluid inlet;
• a fluid outlet;
• a first microchannel disposed between the fluid inlet and the fluid outlet and having a height h1 in a range of 1 to 1000 microns and a length li;
• and
• a mesofluidic collection chamber comprising a height h3 in the range of 2 mm to 20 mm and distally coupled to the first microchannel on a first side of the mesofluidic collection chamber;
• (b) an input chamber operatively coupled to the first microchannel via the fluid inlet;
• and
• (c) an output chamber operatively coupled to the mesofluidic collection chamber via the fluid outlet,
• the device configured such that the particulates dispersed in the base fluid traverse through the first microchannel and are caused to migrate through the device by a force field applied across one or more dimensions of the first microchannel, and wherein the particulates delaminate from the base fluid, generate lamellar flow lines and are driven into a specific laminate of a plurality of layers of the base fluid flowing within the first microchannel and wherein the particulates follow their respective lamellar flow lines during fluidic expansion from the first microchannel to the mesofluidic collection chamber while entering into the mesofluidic collection chamber, and further wherein at least a portion of the particulates in a portion of the base fluid are collected in the mesofluidic collection chamber.