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US 10,517,999 B2Granted
Hydrophilic coatings through in situ surface polymerization
AssigneeCardiac Pacemakers, Inc.
InventorsJohn Kummailil, Paul V. Grosso, Joseph T. Delaney, Jr.
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Abstract
A medical device for insertion or implantation in a body includes a polymer substrate and a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate. Polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate.
Claims12
A medical device for insertion or implantation in a body, the medical device comprising:
- a polymer substrate;
- and
- a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate, wherein polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate to form a lubricious, hydrophilic layer, the polymer chains cross-linked with a cross-linking compound including at least one compound selected from the group of poly(ethylene glycol) diacrylate, poly(ethylene glycol) dimethacrylate and neopentylglycol diacrylate.
A medical device for insertion or implantation in a body, the medical device comprising:
- a polymer substrate;
- a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate, wherein polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate to form a lubricious, hydrophilic layer;
- and
- a polymer layer disposed on the layer of poly(vinyl pyrrolidone-alt-maleic anhydride), the polymer layer including at least one polymer selected from the group of poly(vinyl acetate), poly(vinylpyrrolidone) and poly(acrylic acid).
1 more element
Dependencies are inferred from the claim text.