Optical imaging probes, optical imaging systems, methods of optical imaging, and methods of using optical imaging probes
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsSanjiv S. Gambhir, Zhen Cheng, Sri-rajasekhar Kothapalli, Hongguang Liu
Life of this patent
Estimating the term…
Abstract
Embodiments of the present disclosure provide for radionuclide probes, methods of using the radionuclide probes, methods of detecting an optical signal from radionuclides, methods of detecting an optical signal from a quantum dot(s) that receives optical energy from a radionuclide(s), system for analyzing optical energy emitted by a radionuclide(s), system for imaging a target within a living subject or a sample, methods of imaging a disease or condition, and the like.
Claims23
A method of imaging a target within a living subject or a sample comprising:
- introducing one or more radionuclide probes into the living subject or sample;
- and
- detecting low energy photons from one or more radionuclide probes as optical signals, wherein the low energy photon have an energy of less than 0.005 keV.
A system for imaging a target within a living subject or a sample, comprising:
- an optical detection system configured to detect low energy photons from one or more radionuclides as optical signals within said living subject or sample, wherein the low energy photon have an energy of less than 0.005 keV;
- and
- an optical signal processing system configured to provide images based upon the optical signal;
- wherein the optical detection system comprises photonic devices to detect and to transmit low energy photons generated by one or more radionuclide as optical signals.
A method for analyzing an optical signal emitted by one or more radionuclides, comprising:
- detecting low energy photons from one or more radionuclides as optical signals, wherein the low energy photon have an energy of less than 0.005 keV;
- and
- processing data corresponding to the detected optical signals to provide information about the optical signal emitted by the one or more radionuclides.
Dependencies are inferred from the claim text.