Nucleophile-triggered degradable materials and methods of making and using the same
AssigneeGeorgia Tech Research Corporation
InventorsM. G. Finn, Cody James Higginson
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Abstract
Disclosed herein are degradable materials comprising the reaction product of an oxanorbornadiene crosslinker or derivative thereof and a multivalent nucleophile-terminated compound, wherein the reaction product is a degradable elastic solid capable of entraining cargo. Also disclosed herein are degradable materials comprising a polymeric and hyperbranched crosslinked material made with oxanorbornadiene linkage that can be activated for cleavage at a predetermined rate by addition of a nucleophile. Also disclosed herein are methods of making and using the same.
Claims16
A degradable material comprising:
- the reaction product of
- an oxanorbornadiene crosslinker or derivative thereof;
- and
- a multivalent nucleophile-terminated compound;
- wherein the reaction product is a degradable elastic solid capable of entraining cargo.
A method for producing a degradable material, the method comprising:
- combining a solution of a multivalent nucleophile-terminated compound and an oxanorbornadiene crosslinker to yield elastic solids capable of entraining cargo,
- wherein the reaction between the multivalent nucleophile-terminated compound and oxanorbornadiene trigger programmed fragmentation of adducts, and
- wherein the programmed fragmentation of adducts causes the material to degrade.
Dependencies are inferred from the claim text.