Pharmaceutical composition for treating and/or preventing esophageal stenosis
AssigneeKagoshima University
InventorsAkio Ido, Hirohito Tsubouchi, Yuga Komaki
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Abstract
According to this invention, the following are provided: a pharmaceutical composition for treating and/or preventing esophageal stenosis, comprising an HGF protein as an active ingredient (wherein the HGF protein may be a polypeptide that is any one of the following: (a) a polypeptide comprising the amino acid sequence shown in SEQ ID NO: 2; (b) a polypeptide comprising an amino acid sequence shown in SEQ ID NO: 2 in which one to several amino acids are deleted, substituted, or added; or (c) a polypeptide comprising an amino acid sequence having at least 90% identity with the amino acid sequence shown in SEQ ID NO: 2; and a stent comprising the pharmaceutical composition.
Claims12
A method for inhibiting esophageal stenosis in a patient having an esophageal ulcer, comprising administering to the patient a pharmaceutical composition comprising hepatocyte growth factor (HGF) protein in a dosage effective to inhibit esophageal stenosis.
A method for inhibiting esophageal stenosis in a patient that has undergone endoscopic submucosal dissection, comprising administering to the patient a pharmaceutical composition comprising hepatocyte growth factor (HGF) protein in a dosage effective to inhibit esophageal stenosis.
Dependencies are inferred from the claim text.