Compositions and methods for viral embolization
AssigneeSillajen, Inc.
InventorsTae Ho Hwang, Nam Hee Lee, Mong Cho, Ungbae Jeon, Doo Jin Byun
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to oncolytic viruses for use transcatheter arterial viroembolization methods. The present disclosure also provides composition with such oncolytic viruses in combination with a biocompatible microparticle or hydrophilic polymer gel agent suitable for active embolization. The present disclosure further provides methods of transcatheter arterial viroembolization using such oncolytic viruses and compositions preferably in a manner that debulks tumor.
Claims17
A composition comprising an oncolytic vaccinia virus or an oncolytic Herpes simplex virus type 1 (HSV-1) and an agent for active embolization, wherein the active embolization agent is selected from degradable starch, polyvinyl alcohol, gelatin foam, and sulfonated polyvinyl alcohol hydrogel.
Dependencies are inferred from the claim text.