Method for healing of an infected acne lesion without scarring
AssigneeFoamix Pharmaceuticals Ltd.
InventorsDov Tamarkin, Elana Gazal, Rita Keynan, Meir Eini, David Schuz
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Abstract
Methods of treatment and dosage regimes using hydrophobic gel or foam compositions comprising a tetracycline antibiotic for accelorating the return of skin integrity and or in treating or alleviating a disorder including impetigo, acne, rosacea, a skin disease caused by a bacteria or a tetracycline antibiotic responsive disease, wherein the foam composition or gel is administered topically to a target area on a subject having the disorder and wherein the target area comprises an area of skin, or mucosa or an eye.
Claims8
A method for healing of an infected acne lesion without scarring, comprising topically administering at least once daily an effective amount of a minocycline antibiotic foam to an infected acne lesion, wherein the minocycline antibiotic foam is produced from a foamable composition upon addition of a liquefied or compressed gas propellant, the foamable composition comprising:
- (a) 60% to 90% by weight of one or more hydrophobic oils selected from the group consisting of a mineral oil, a soybean oil, a coconut oil, cyclomethicone, and a mixture of two or more thereof;
- (b) a wax selected from the group consisting of a beeswax, a hydrogenated castor oil, and a mixture thereof;
- (c) at least one solid fatty alcohol having a carbon chain length of 14 to 22 carbons;
- (d) at least one solid fatty acid having a carbon chain length of 12 to 28 carbons;
- and
- (e) 0.2% to 10% by weight of a minocycline;
- and
- wherein the foamable composition does not comprise a surfactant.
Dependencies are inferred from the claim text.